Role of lipid profile, apolipoproteins, and their ratio for prediction of cardiovascular disease in essential hypertension

Background and Aim of Study: Dyslipidemia is a risk factor for cardiovascular disease, lipid metabolism changes are linked to essential hypertension. The aim the study: investigate significance parameters, apolipoproteins, their ratio in predicting disease among individuals with Material Methods: 250 patients hypertension healthy control subjects were enrolled this case-control study serum lipids apolipoproteins analyzed. Differences between cases controls examined using independent sample t-test and, p-value <0.05 was considered significant. Results: In hypertensive group, fasting blood glucose (FBG), total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C), very (VLDL-C), apolipoprotein B100 (Apo B100) Apo B100/Apo A1 increased significantly compared subjects. Essential had decreased levels A1) high-density (HDL-C) controls. Moreover, age, body mass index (BMI), FBG, TC, TG, LDL-C, VLDL-C, as well ratio, positively correlated both systolic pressure (SBP) diastolic (DBP), but HDL-C negatively There significant positive correlation apo SBP people DBP showed association, however, it not statistically Conclusions: dyslipidemia an elevated at development disease.